Cerebrolysin Ameliorates Focal Cerebral Ischemia Injury Through Neuroinflammatory Inhibition via CREB/PGC-1α Pathway

• Main Authors: Xin Guan (Author), Yunjie Wang (Author), Guoyin Kai (Author), Shunyi Zhao (Author), Tingyu Huang (Author), Youzhen Li (Author), Yuan Xu (Author), Luyong Zhang (Author), Tao Pang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuroinflammation is one of the important factors aggravating brain injury after ischemic stroke. We aimed to investigate the effects of cerebrolysin (CBL) on neuroinflammation in vivo and in vitro and the underlying mechanisms. The gene expressions of pro-inflammatory factors and anti-inflammatory...