Sporadic amyotrophic lateral sclerosis (SALS) - skeletal muscle response to cerebrospinal fluid from SALS patients in a rat model

• Ngā kaituhi matua: Shruthi Shanmukha (Author), Gayathri Narayanappa (Author), Atchayaram Nalini (Author), Phalguni Anand Alladi (Author), Trichur R. Raju (Author)
• Hōputu: Pukapuka
• I whakaputaina: The Company of Biologists, 2018-04-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Skeletal muscle atrophy is the most prominent feature of amyotrophic lateral sclerosis (ALS), an adult-onset neurodegenerative disease of motor neurons. However, the contribution of skeletal muscle to disease progression remains elusive. Our previous studies have shown that intrathecal injection of...