Sporadic amyotrophic lateral sclerosis (SALS) - skeletal muscle response to cerebrospinal fluid from SALS patients in a rat model

• Main Authors: Shruthi Shanmukha (Author), Gayathri Narayanappa (Author), Atchayaram Nalini (Author), Phalguni Anand Alladi (Author), Trichur R. Raju (Author)
• Format: Book
• Published: The Company of Biologists, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Skeletal muscle atrophy is the most prominent feature of amyotrophic lateral sclerosis (ALS), an adult-onset neurodegenerative disease of motor neurons. However, the contribution of skeletal muscle to disease progression remains elusive. Our previous studies have shown that intrathecal injection of...