Indigenous microbiota protects development of medication-related osteonecrosis induced by periapical disease in mice

• Main Authors: Wen Du (Author), Mengyu Yang (Author), Terresa Kim (Author), Sol Kim (Author), Drake W. Williams (Author), Maryam Esmaeili (Author), Christine Hong (Author), Ki-Hyuk Shin (Author), Mo K. Kang (Author), No-Hee Park (Author), Reuben H. Kim (Author)
• Format: Book
• Published: Nature Publishing Group, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Bacterial infection is a common finding in patients, who develop medication-related osteonecrosis of the jaw (MRONJ) by the long-term and/or high-dose use of anti-resorptive agents such as bisphosphonate (BPs). However, pathological role of bacteria in MRONJ development at the early stage r...