Inhibition of Peroxiredoxin 6 PLA2 Activity Decreases Oxidative Stress and the Severity of Acute Lung Injury in the Mouse Cecal Ligation and Puncture Model

• Главные авторы: Aron B. Fisher (Автор), Chandra Dodia (Автор), Jian-Qin Tao (Автор), Sheldon I. Feinstein (Автор), Shampa Chatterjee (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2021-10-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

The use of agents to inhibit the production of reactive oxygen species (ROS) has been proposed for the treatment of Acute Lung Injury (ALI). However, this approach also inhibits the bactericidal activity of polymorphonuclear leucocytes (PMN) and other cells, raising the possibility of aggravating lu...