DNA methylation patterns of imprinting centers for H19, SNRPN, and KCNQ1OT1 in single-cell clones of human amniotic fluid mesenchymal stem cell

• Main Authors: Hsiu-Huei Peng (Author), Shuenn-Dyh Chang (Author), An-Shine Chao (Author), Chao-Nin Wang (Author), Po-Jen Cheng (Author), Shiaw-Min Hwang (Author), Tzu-Hao Wang (Author)
• Format: Book
• Published: Elsevier, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To test the hypothesis that human amniotic fluid mesenchymal stem cells contain a unique epigenetic signature in imprinting centers of H19, SNRPN, and KCNQ1OT1 during in vitro cell culture. Materials and Methods: By bisulfite genomic sequencing, we analyzed the imprinting centers of three...