HMM-based profiling identifies the binding to divalent cations and nucleotides as common denominators of suramin targets
Introduction: Suramin is one of the pharmacopeia's most promiscuous drugs. Originally developed for African trypanosomiasis, suramin was also used for onchocerciasis and it has been proposed as an anticancer agent, antiviral drug, therapy for arthritis, autism, and antidote for snake bites. Tar...
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