A model-informed approach to assess the risk of immune checkpoint inhibitor-induced autoimmune myocarditis

• Main Authors: Solveig A. van der Vegt (Author), Ying-Jie Wang (Author), Liudmila Polonchuk (Author), Ken Wang (Author), Sarah L. Waters (Author), Ruth E. Baker (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Immune checkpoint inhibitors (ICIs), as a novel immunotherapy, are designed to modulate the immune system to attack malignancies. Despite their promising benefits, immune-related adverse events (IRAEs) may occur, and incidences are bound to increase with surging demand of this class of drugs in trea...