In-depth comparison of cell-based methodological approaches to determine drug susceptibility of visceral Leishmania isolates.

• Autori principali: Sarah Hendrickx (Autore), Lieselotte Van Bockstal (Autore), Guy Caljon (Autore), Louis Maes (Autore)
• Natura: Libro
• Pubblicazione: Public Library of Science (PLoS), 2019-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Monitoring the drug susceptibility of Leishmania isolates still largely relies on standard in vitro cell-based susceptibility assays using (patient-isolated) promastigotes for infection. Although this assay is widely used, no fully standardized/harmonized protocol is yet available hence resulting in...