Leptin interferes with 3',5'-Cyclic Adenosine Monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells

• Main Authors: HoYuen Basil (Author), Cheng Linan (Author), Chen Junling (Author), Poon Song (Author), Lin Qing (Author), Leung Peter CK (Author)
• Format: Book
• Published: BMC, 2009-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Obesity has been linked to an increased risk of female infertility. Leptin, an adipocytokine which is elevated during obesity, may influence gonadal function through modulating steroidogenesis in granulosa cells.</p> <p>M...