Identification of potential inhibitors of Zika virus NS5 RNA-dependent RNA polymerase through virtual screening and molecular dynamic simulations

• Main Authors: Noreen (Author), Roshan Ali (Author), Syed Lal Badshah (Author), Muhammad Faheem (Author), Sumra Wajid Abbasi (Author), Riaz Ullah (Author), Ahmed Bari (Author), Syed Babar Jamal (Author), Hafiz Majid Mahmood (Author), Adnan Haider (Author), Sajjad Haider (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Zika virus (ZIKV) is one of the mosquito borne flavivirus with several outbreaks in past few years in tropical and subtropical regions. The non-structural proteins of flaviviruses are suitable active targets for inhibitory drugs due to their role in pathogenicity. In ZIKV, the non-structural protein...