Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits
The eye uses vitamin A as a cofactor to sense light and, during this process, some vitamin A molecules dimerize, forming vitamin A dimers. A striking chemical signature of retinas undergoing degeneration in major eye diseases such as age-related macular degeneration (AMD) and Stargardt disease is th...
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The Company of Biologists,
2015-02-01T00:00:00Z.
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