The first activation study of a δ-carbonic anhydrase: TweCAδ from the diatom Thalassiosira weissflogii is effectively activated by amines and amino acids

• मुख्य लेखकों: Andrea Angeli (लेखक), Fatmah A. S. Alasmary (लेखक), Sonia Del Prete (लेखक), Sameh M. Osman (लेखक), Zeid AlOthman (लेखक), William A. Donald (लेखक), Clemente Capasso (लेखक), Claudiu T. Supuran (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The activation of the δ-class carbonic anhydrase (CAs, EC 4.2.1.1) from the diatom Thalassiosira weissflogii (TweCAδ) was investigated using a panel of natural and non-natural amino acids and amines. The most effective activator of TweCAδ was d-Tyr (KA of 51 nM), whereas several other amino acids an...