The Multi-target Effects of CNI-1493: Convergence of Antiamylodogenic and Antiinflammatory Properties in Animal Models of Alzheimer's Disease

• Main Authors: Roman Sankowski (Author), Arne Herring (Author), Kathy Keyvani (Author), Kathrin Frenzel (Author), Jinyu Wu (Author), Stephan Röskam (Author), Carmen Noelker (Author), Michael Bacher (Author), Yousef Al-Abed (Author)
• Formato: Livro
• Publicado em: BMC, 2016-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract After several decades of Alzheimer's disease (AD) research and failed clinical trials, one can speculate that targeting a single pathway is not sufficient. However, a cocktail of novel therapeutics will constitute a challenging clinical trial. A more plausible approach will capitalize...