Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC)

Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC)

Among current novel druggable targets, protein-protein interactions (PPIs) are of considerable and growing interest. Diacylglycerol kinase α (DGKα) interacts with focal adhesion kinase (FAK) band 4.1-ezrin-radixin-moesin (FERM) domain to induce the phosphorylation of FAK Tyr397 site and promotes the...

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Main Authors: Jie Chen (Author), Yan Wang (Author), Di Zhao (Author), Lingyuan Zhang (Author), Weimin Zhang (Author), Jiawen Fan (Author), Jinting Li (Author), Qimin Zhan (Author)
Format: Book
Published: Elsevier, 2021-01-01T00:00:00Z.
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