CB2R Deficiency Exacerbates Imiquimod-Induced Psoriasiform Dermatitis and Itch Through the Neuro-Immune Pathway

• Main Authors: Li Li (Author), Xin Liu (Author), Wenqiang Ge (Author), Chao Chen (Author), Yuqiong Huang (Author), Zilin Jin (Author), Muouyang Zhan (Author), Xiaoru Duan (Author), Xinxin Liu (Author), Yi Kong (Author), Jian Jiang (Author), Xuemei Li (Author), Xin Zeng (Author), Fei Li (Author), Shibin Xu (Author), Man Li (Author), Hongxiang Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Cannabinoid receptor 2 (CB2R) is a potential target for anti-inflammatory and pain therapeutics given its significant immunomodulatory and analgesic effects. However, the role of CB2R in imiquimod (IMQ)-induced psoriasiform dermatitis (PsD) and itch is poorly understood.Objective: To inv...