Eluxadoline Loaded Solid Lipid Nanoparticles for Improved Colon Targeting in Rat Model of Ulcerative Colitis

• Main Authors: Md. Khalid Anwer (Author), Mohammed Muqtader Ahmed (Author), Mohammed F. Aldawsari (Author), Saad Alshahrani (Author), Farhat Fatima (Author), Mohd Nazam Ansari (Author), Najeeb Ur Rehman (Author), Ramadan I. Al-Shdefat (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the current study was to evaluate the therapeutics potential of eluxadoline (ELX) loaded solid lipid nanoparticles (SLNs) in ulcerative colitis. ELX loaded SLNs were prepared using three different lipids according to the solvent emulsification technique. The optimization of prepared SLNs...