Elucidating heavy/light chain pairing preferences to facilitate the assembly of bispecific IgG in single cells

Multiple strategies have been developed to facilitate the efficient production of bispecific IgG (BsIgG) in single host cells. For example, we previously demonstrated near quantitative (≥90%) formation of BsIgG of different species and isotypes by combining 'knob-into-hole' mutations for h...

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Bibliographic Details
Main Authors: Kamal Kishore Joshi (Author), Wilson Phung (Author), Guanghui Han (Author), Yiyuan Yin (Author), Ingrid Kim (Author), Wendy Sandoval (Author), Paul J. Carter (Author)
Format: Book
Published: Taylor & Francis Group, 2019-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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