Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis

Tyrosine kinase inhibitors (TKIs) are anticancer drugs with a lesser toxicity than classical chemotherapeutic agents but still with a narrow therapeutic window. While hepatotoxicity is known for most TKIs, underlying mechanisms remain mostly unclear. We therefore aimed at investigating mechanisms of...

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Bibliographic Details
Main Authors: Franziska Paech (Author), Jamal Bouitbir (Author), Stephan Krähenbühl (Author)
Format: Book
Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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