Pleiotrophin Interaction with Synthetic Glycosaminoglycan Mimetics

• Váldodahkkit: Jonathan R. Miles (Dahkki), Xu Wang (Dahkki), Jose L. de Paz (Dahkki), Pedro M. Nieto (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2022-04-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Chondroitin sulfate (CS) E is the natural ligand for pleiotrophin (PTN) in the central nervous system (CNS) of the embryo. Some structures of PTN in solution have been solved, but no precise location of the binding site has been reported yet. Using ¹⁵N-labelled PTN and HSQC NM...