Mismatch repair deficiency is associated with specific morphologic features and frequent loss of ARID1A expression in ovarian clear cell carcinoma

• Main Authors: Huijuan Ge (Author), Yaoxin Xiao (Author), Guangqi Qin (Author), Yanzi Gu (Author), Xu Cai (Author), Wenhua Jiang (Author), Xiaoyu Tu (Author), Wentao Yang (Author), Rui Bi (Author)
• Format: Book
• Published: BMC, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ovarian clear cell carcinoma (OCCC) is the second subtype of ovarian epithelial carcinoma reported to be closely related to Lynch syndrome (LS). ARID1A mutation is an important pathogenetic mechanism in OCCC that leads to loss of ARID1A expression in approximately half of OCCCs....