Myocardial chemokine expression and intensity of myocarditis in Chagas cardiomyopathy are controlled by polymorphisms in CXCL9 and CXCL10.

• Автори: Luciana Gabriel Nogueira (Автор), Ronaldo Honorato Barros Santos (Автор), Barbara Maria Ianni (Автор), Alfredo Inácio Fiorelli (Автор), Eliane Conti Mairena (Автор), Luiz Alberto Benvenuti (Автор), Amanda Frade (Автор), Eduardo Donadi (Автор), Fabrício Dias (Автор), Bruno Saba (Автор), Hui-Tzu Lin Wang (Автор), Abilio Fragata (Автор), Marcelo Sampaio (Автор), Mario Hiroyuki Hirata (Автор), Paula Buck (Автор), Charles Mady (Автор), Edimar Alcides Bocchi (Автор), Noedir Antonio Stolf (Автор), Jorge Kalil (Автор), Edecio Cunha-Neto (Автор)
• Формат: Книга
• Опубліковано: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

BACKGROUND: Chronic Chagas cardiomyopathy (CCC), a life-threatening inflammatory dilated cardiomyopathy, affects 30% of the approximately 8 million patients infected by Trypanosoma cruzi. Even though the Th1 T cell-rich myocarditis plays a pivotal role in CCC pathogenesis, little is known about the...