Analytical and clinical performance of the CDC real time RT-PCR assay for detection and typing of dengue virus.

• Main Authors: Gilberto A Santiago (Author), Edgardo Vergne (Author), Yashira Quiles (Author), Joan Cosme (Author), Jesus Vazquez (Author), Juan F Medina (Author), Freddy Medina (Author), Candimar Colón (Author), Harold Margolis (Author), Jorge L Muñoz-Jordán (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue is an acute illness caused by the positive-strand RNA dengue virus (DENV). There are four genetically distinct DENVs (DENV-1-4) that cause disease in tropical and subtropical countries. Most patients are viremic when they present with symptoms; therefore, RT-PCR has been increasingly used in...