Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach

• Main Authors: Chiara Bianca Maria Platania (Author), Luisa eDi Paola (Author), Gian Marco eLeggio (Author), Giovanni Luca eRomano (Author), Filippo eDrago (Author), Salvatore eSalomone (Author), Claudio eBucolo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Anti-angiogenic agents are biological drugs used for treatment of retinal neovascular degenerative diseases. In this study, we aimed at in-silico analysis of interaction of vascular endothelial growth factor A (VEGFA), the main mediator of angiogenesis, with binding domains of anti-angiogenic agents...