Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach

• Hoofdauteurs: Chiara Bianca Maria Platania (Auteur), Luisa eDi Paola (Auteur), Gian Marco eLeggio (Auteur), Giovanni Luca eRomano (Auteur), Filippo eDrago (Auteur), Salvatore eSalomone (Auteur), Claudio eBucolo (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2015-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Anti-angiogenic agents are biological drugs used for treatment of retinal neovascular degenerative diseases. In this study, we aimed at in-silico analysis of interaction of vascular endothelial growth factor A (VEGFA), the main mediator of angiogenesis, with binding domains of anti-angiogenic agents...