Learn-confirm in model‐informed drug development: Assessing an immunogenicity quantitative systems pharmacology platform
Abstract Immunogenicity against therapeutic proteins frequently causes attrition owing to its potential impact on pharmacokinetics, pharmacodynamics, efficacy, and safety. Predicting immunogenicity is complex because of its multifactorial drivers, including compound properties, subject characteristi...
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Wiley,
2023-02-01T00:00:00Z.
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