Comparative genomics of Leishmania donovani progeny from genetic crosses in two sand fly species and impact on the diversity of diagnostic and vaccine candidates.

• Main Authors: Jovana Sádlová (Author), Matthew Yeo (Author), David S Mateus (Author), Jody Phelan (Author), Le Anh Hai (Author), Tapan Bhattacharyya (Author), Stefan Kurtev (Author), Ondrej Sebesta (Author), Jitka Myskova (Author), Veronika Seblova (Author), Björn Andersson (Author), Paola Florez de Sessions (Author), Petr Volf (Author), Michael A Miles (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sand fly transmitted Leishmania species are responsible for severe, wide ranging, visceral and cutaneous leishmaniases. Genetic exchange can occur among natural Leishmania populations and hybrids can now be produced experimentally, with limitations. Feeding Phlebotomus orientalis or Phlebotomus arge...