Upregulation of Phosphodiesterase 2A Augments T Cell Activation by Changing cGMP/cAMP Cross-Talk

• Asıl Yazarlar: Roberta Kurelic (Yazar), Paula F. Krieg (Yazar), Jana K. Sonner (Yazar), Gloria Bhaiyan (Yazar), Gustavo C. Ramos (Yazar), Stefan Frantz (Yazar), Manuel A. Friese (Yazar), Viacheslav O. Nikolaev (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

3',5'-cyclic adenosine monophosphate (cAMP) is well-known for its diverse immunomodulatory properties, primarily inhibitory effects during T cell activation, proliferation, and production of pro-inflammatory cytokines. A decrease in cAMP levels, due to the hydrolyzing activity of phosphodi...