Boosting Akt Pathway by Rupatadine Modulates Th17/Tregs Balance for Attenuation of Isoproterenol-Induced Heart Failure in Rats

• Main Authors: Lamiaa A. Ahmed (Author), Ahmed F. Mohamed (Author), Enas A. Abd El-Haleim (Author), Dalia M. El-Tanbouly (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Disruption of Th17/Tregs homeostasis plays a crucial role in governing the immune response during myocardial fibrosis and its progression to heart failure. The present study aimed to assess for the first time the possible protection afforded by rupatadine against isoproterenol-induced heart failure...