Functionalized lipid nanoparticles modulate the blood-brain barrier and eliminate α-synuclein to repair dopamine neurons

• Váldodahkkit: Xiaomei Wu (Dahkki), Renxiang Yuan (Dahkki), Yichong Xu (Dahkki), Kai Wang (Dahkki), Hong Yuan (Dahkki), Tingting Meng (Dahkki), Fuqiang Hu (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2024-04-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The challenge in the clinical treatment of Parkinson's disease lies in the lack of disease-modifying therapies that can halt or slow down the progression. Peptide drugs, such as exenatide (Exe), with potential disease-modifying efficacy, have difficulty in crossing the blood-brain barrier (BBB)...