Biased, Bitopic, Opioid-Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction

This paper proposes the design of combination opioid-adrenergic tethered compounds to enhance efficacy and specificity, lower dosage, increase duration of activity, decrease side effects, and reduce risk of developing tolerance and/or addiction. Combinations of adrenergic and opioid drugs are someti...

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Main Author: Robert Root-Bernstein (Author)
Format: Book
Published: MDPI AG, 2022-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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