BRCA immunohistochemistry for screening of BRCA mutation in epithelial ovarian cancer patients

• Hauptverfasser: Tarinee Manchana (Verfasst von), Patou Tantbirojn (Verfasst von), Natkrita Pohthipornthawat (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2020-08-01T00:00:00Z.
• Schlagworte: article
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To evaluate BRCA1/2 immunohistochemistry (IHC) as a screening test for germline BRCA1/2 in epithelial ovarian cancer (EOC), tumor tissue from 105 EOC patients who had germline BRCA mutations, including 9 BRCA1 mutations, 6 BRCA2 mutations and 90 no BRCA mutations, were studied. Paraffin-embedded tis...