Therapeutic Effects of Simultaneous Delivery of Nerve Growth Factor mRNA and Protein via Exosomes on Cerebral Ischemia

• Главные авторы: Jialei Yang (Автор), Shipo Wu (Автор), Lihua Hou (Автор), Danni Zhu (Автор), Shimin Yin (Автор), Guodong Yang (Автор), Yongjun Wang (Автор)
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• Опубликовано: Elsevier, 2020-09-01T00:00:00Z.
• Предметы: article
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Stroke is the leading neurological cause of death and disability all over the world, with few effective drugs. Nerve growth factor (NGF) is well known for its multifaceted neuroprotective functions post-ischemia. However, the lack of an efficient approach to systemically deliver bioactive NGF into i...