Chitosan-Hyaluronan Nanoparticles for Vinblastine Sulfate Delivery: Characterization and Internalization Studies on K-562 Cells

Chitosan-Hyaluronan Nanoparticles for Vinblastine Sulfate Delivery: Characterization and Internalization Studies on K-562 Cells

In the present study, we developed chitosan/hyaluronan nanoparticles (CS/HY NPs) for tumor targeting with vinblastine sulfate (VBL), that can be directed to the CD44 transmembrane receptor, over-expressed in cancer cells. NPs were prepared by coating with HY-preformed chitosan/tripolyphosphate (CS/T...

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Main Authors: Carmela Cannavà (Author), Federica De Gaetano (Author), Rosanna Stancanelli (Author), Valentina Venuti (Author), Giuseppe Paladini (Author), Francesco Caridi (Author), Corneliu Ghica (Author), Vincenza Crupi (Author), Domenico Majolino (Author), Guido Ferlazzo (Author), Silvana Tommasini (Author), Cinzia Anna Ventura (Author)
Format: Book
Published: MDPI AG, 2022-04-01T00:00:00Z.
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