Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats

• Main Authors: Víctor Fernández-Dueñas (Author), Jaume J. Taura (Author), Martin Cottet (Author), Maricel Gómez-Soler (Author), Marc López-Cano (Author), Catherine Ledent (Author), Masahiko Watanabe (Author), Eric Trinquet (Author), Jean-Philippe Pin (Author), Rafael Luján (Author), Thierry Durroux (Author), Francisco Ciruela (Author)
• Format: Book
• Published: The Company of Biologists, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease (PD) is a dopaminergic-related pathology in which functioning of the basal ganglia is altered. It has been postulated that a direct receptor-receptor interaction - i.e. of dopamine D2 receptor (D2R) with adenosine A2A receptor (A2AR) (forming D2R-A2AR oligomers) - finely reg...