Poly(lactic-co-glycolic acid) Nanoparticles Encapsulating the Prenylated Flavonoid, Xanthohumol, Protect Corneal Epithelial Cells from Dry Eye Disease-Associated Oxidative Stress

• Main Authors: Anita Kirti Ghosh (Author), Rubina Thapa (Author), Harsh Nilesh Hariani (Author), Michael Volyanyuk (Author), Sean David Ogle (Author), Karoline Anne Orloff (Author), Samatha Ankireddy (Author), Karen Lai (Author), Agnė Žiniauskaitė (Author), Evan Benjamin Stubbs (Author), Giedrius Kalesnykas (Author), Jenni Johanna Hakkarainen (Author), Kelly Ann Langert (Author), Simon Kaja (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress is a known contributor to the progression of dry eye disease pathophysiology, and previous studies have shown that antioxidant intervention is a promising therapeutic approach to reduce the disease burden and slow disease progression. In this study, we evaluated the pharmacological...