Importance of Mesoporous Silica Particle Size in the Stabilization of Amorphous Pharmaceuticals-The Case of Simvastatin

• Main Authors: Justyna Knapik-Kowalczuk (Author), Daniel Kramarczyk (Author), Krzysztof Chmiel (Author), Jana Romanova (Author), Kohsaku Kawakami (Author), Marian Paluch (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this paper, the role of mesoporous silica (MS) particle size in the stabilization of amorphous simvastatin (SVT) is revealed. For inhibiting recrystallization of the supercooled drug, the two MS materials (Syloid^® XDP 3050 and Syloid^® 244 FP) were emp...