Baicalein: A potential GLP-1R agonist improves cognitive disorder of diabetes through mitophagy enhancement

• Main Authors: Na Liu (Author), Xin Cui (Author), Wenhui Yan (Author), Tingli Guo (Author), Zhuanzhuan Wang (Author), Xiaotong Wei (Author), Yuzhuo Sun (Author), Jieyun Liu (Author), Cheng Xian (Author), Weina Ma (Author), Lina Chen (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is increasing evidence that the activation of glucagon-like peptide-1 receptor (GLP-1R) can be used as a therapeutic intervention for cognitive disorders. Here, we have screened GLP-1R targeted compounds from Scutellaria baicalensis, which revealed baicalein is a potential GLP-1R small-molecul...