Lyplal1 is dispensable for normal fat deposition in mice

• Main Authors: Rachel A. Watson (Author), Amy S. Gates (Author), Elizabeth H. Wynn (Author), Fiona E. Calvert (Author), Amandine Girousse (Author), Christopher J. Lelliott (Author), Inês Barroso (Author)
• Format: Book
• Published: The Company of Biologists, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Genome-wide association studies (GWAS) have detected association between variants in or near the Lysophospholipase-like 1 (LYPLAL1) locus and metabolic traits, including central obesity, fatty liver and waist-to-hip ratio. LYPLAL1 is also known to be upregulated in the adipose tissue of obese patien...