Lyplal1 is dispensable for normal fat deposition in mice

• Egile Nagusiak: Rachel A. Watson (Egilea), Amy S. Gates (Egilea), Elizabeth H. Wynn (Egilea), Fiona E. Calvert (Egilea), Amandine Girousse (Egilea), Christopher J. Lelliott (Egilea), Inês Barroso (Egilea)
• Formatua: Liburua
• Argitaratua: The Company of Biologists, 2017-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Genome-wide association studies (GWAS) have detected association between variants in or near the Lysophospholipase-like 1 (LYPLAL1) locus and metabolic traits, including central obesity, fatty liver and waist-to-hip ratio. LYPLAL1 is also known to be upregulated in the adipose tissue of obese patien...