Enhancements of Bcl-2/mTOR/ERK1/2 activities by antioxidant mechanisms confer cardioprotection on Ginkgo biloba supplement against isoprenaline-induced myocardial infarction in rats

• Main Authors: Jerome Ndudi Asiwe (Author), Benneth Ben-Azu (Author), Godwin D. Yovwin (Author), Santos Ehizokhale Ehebha (Author), Vincent-Junior Onoriode Igben (Author), Endurance Efe Ahama (Author), Akpevwoghene Agbatutu (Author), Tarela Melish Elias Daubry (Author), Benjamin Oritsemuelebi (Author), Emuesiri Goodies Moke (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Myocyte necrosis and apoptosis can be severely induced by acute adrenergic stimulation due to the activation of several cell signalling pathways. However, uncertainty exists regarding the potential cardioprotective effects of Ginkgo biloba (GBS), a Chinese herbal supplement rich with ant...