Myosin Light Chain Kinase: A Potential Target for Treatment of Inflammatory Diseases

• Main Authors: Yongjian Xiong (Author), Chenou Wang (Author), Liqiang Shi (Author), Liang Wang (Author), Zijuan Zhou (Author), Dapeng Chen (Author), Jingyu Wang (Author), Huishu Guo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myosin light chain kinase (MLCK) induces contraction of the perijunctional apical actomyosin ring in response to phosphorylation of the myosin light chain. Abnormal expression of MLCK has been observed in respiratory diseases, pancreatitis, cardiovascular diseases, cancer, and inflammatory bowel dis...