The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB₂ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy

• Main Authors: Deng Liting (Author), Guindon Josée (Author), Vemuri V (Author), Thakur Ganesh A (Author), White Fletcher A (Author), Makriyannis Alexandros (Author), Hohmann Andrea G (Author)
• Format: Book
• Published: SAGE Publishing, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Chemotherapeutic agents produce dose-limiting peripheral neuropathy through mechanisms that remain poorly understood. We previously showed that AM1710, a cannabilactone CB₂ agonist, produces antinociception wit...