Administration of adiponectin receptor agonist AdipoRon relieves cancer cachexia by mitigating inflammation in tumour‐bearing mice

• Main Authors: Isabelle S. Massart (Author), Axell‐Natalie Kouakou (Author), Nathan Pelet (Author), Pascale Lause (Author), Olivier Schakman (Author), Audrey Loumaye (Author), Michel Abou‐Samra (Author), Louise Deldicque (Author), Laure B. Bindels (Author), Sonia M. Brichard (Author), Jean‐Paul Thissen (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer cachexia is a life‐threatening, inflammation‐driven wasting syndrome that remains untreatable. Adiponectin, the most abundant adipokine, plays an important role in several metabolic processes as well as in inflammation modulation. Our aim was to test whether administration...