Losartan Protects the Heart Against Ischemia Reperfusion Injury: Sirtuin3 Involvement
PURPOSE: Sirtuin-3 (SIRT3) deacetylase protects the heart against oxidative stress via survival factors upregulation. Clinical and experimental studies have demonstrated that activation of systemic and local renin-angiotensin system (RAS) is implicated in ischemia-induced cardiac injury. However, th...
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Frontiers Media S.A.,
2015-04-01T00:00:00Z.
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A1234.567 |
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Kopie 1 | Beschikbaar |