Automated Real-Time Tumor Pharmacokinetic Profiling in 3D Models: A Novel Approach for Personalized Medicine

• Main Authors: Jan F. Joseph (Author), Leonie Gronbach (Author), Jill García-Miller (Author), Leticia M. Cruz (Author), Bernhard Wuest (Author), Ulrich Keilholz (Author), Christian Zoschke (Author), Maria K. Parr (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer treatment often lacks individual dose adaptation, contributing to insufficient efficacy and severe side effects. Thus, personalized approaches are highly desired. Although various analytical techniques are established to determine drug levels in preclinical models, they are limited in the aut...