HPLC-Based Analysis of Impurities in Sapropterin Branded and Generic Tablets

• Main Authors: Emanuela Scudellaro (Author), Luciana Tartaglione (Author), Fabio Varriale (Author), Carmela Dell'Aversano (Author), Orazio Taglialatela-Scafati (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This work was aimed at the definition of a chromatographic method able to separate and quantify impurities present in sapropterin-containing drugs during an accelerated stability study. The chromatographic method was applied to the orphan drug Kuvan^® and to its corresponding g...