eToxPred: a machine learning-based approach to estimate the toxicity of drug candidates

• Principais autores: Limeng Pu (Autor), Misagh Naderi (Autor), Tairan Liu (Autor), Hsiao-Chun Wu (Autor), Supratik Mukhopadhyay (Autor), Michal Brylinski (Autor)
• Formato: Livro
• Publicado em: BMC, 2019-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background The efficiency of drug development defined as a number of successfully launched new pharmaceuticals normalized by financial investments has significantly declined. Nonetheless, recent advances in high-throughput experimental techniques and computational modeling promise reduction...