eToxPred: a machine learning-based approach to estimate the toxicity of drug candidates

• Main Authors: Limeng Pu (Author), Misagh Naderi (Author), Tairan Liu (Author), Hsiao-Chun Wu (Author), Supratik Mukhopadhyay (Author), Michal Brylinski (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The efficiency of drug development defined as a number of successfully launched new pharmaceuticals normalized by financial investments has significantly declined. Nonetheless, recent advances in high-throughput experimental techniques and computational modeling promise reduction...