Resolvin D1 Modulates the Intracellular VEGF-Related miRNAs of Retinal Photoreceptors Challenged With High Glucose

• Main Authors: Rosa Maisto (Author), Maria Consiglia Trotta (Author), Francesco Petrillo (Author), Sara Izzo (Author), Giovanna Cuomo (Author), Roberto Alfano (Author), Anca Hermenean (Author), Jorge Miquel Barcia (Author), Marilena Galdiero (Author), Chiara Bianca Maria Platania (Author), Claudio Bucolo (Author), Michele D'Amico (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stimulation of retinal photoreceptors with elevated glucose concentration (30 mM) for 96 h, served as diabetic retinopathy in vitro model to study Resolvin D1 (50 nM) effects on neovascularization. VEGF and anti-angiogenic miR-20a-3p, miR-20a-5p, miR-106a-5p, and miR-20b expression was assessed eith...