Nano-in-Micro-Particles Consisting of PLGA Nanoparticles Embedded in Chitosan Microparticles via Spray-Drying Enhances Their Uptake in the Olfactory Mucosa

• Main Authors: Lena Marie Spindler (Author), Andreas Feuerhake (Author), Simone Ladel (Author), Cemre Günday (Author), Johannes Flamm (Author), Nazende Günday-Türeli (Author), Emre Türeli (Author), Günter E. M. Tovar (Author), Katharina Schindowski (Author), Carmen Gruber-Traub (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Fag: article
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Intranasal delivery has gained prominence since 1990, when the olfactory mucosa was recognized as the window to the brain and the central nervous system (CNS); this has enabled the direct site specific targeting of neurological diseases for the first time. Intranasal delivery is a promising route be...