Screening of chemokine receptor CCR4 antagonists by capillary zone electrophoresis

• Main Authors: Zhe Sun (Author), Lin-Jie Tian (Author), Qian Lin (Author), Xiao-Mei Ling (Author), Jun-Hai Xiao (Author), Ying Wang (Author)
• Format: Book
• Published: Elsevier, 2011-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CC chemokine receptor 4 (CCR4) is a kind of G-protein-coupled receptor, which plays a pivotal role in allergic inflammation. The interaction between 2-(2-(4-chloro-phenyl)-5-{[(naphthalen-1-ylmethyl)-carbamoyl]-methyl}-4-oxo-thiazolidin-3-yl)-N-(3-morpholin-4-yl-propyl)-acetamide (S009) and the N-te...