Antivasospastic Effects of Hydroxyfasudil, a Rho-Kinase Inhibitor, After Subarachnoid Hemorrhage

• Hauptverfasser: Shin-ichi Satoh (Verfasst von), Masakazu Takayasu (Verfasst von), Koh Kawasaki (Verfasst von), Ichiro Ikegaki (Verfasst von), Asako Hitomi (Verfasst von), Kazuo Yano (Verfasst von), Masato Shibuya (Verfasst von), Toshio Asano (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2012-01-01T00:00:00Z.
• Schlagworte: article
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We investigated the anti-vasospastic potential of fasudil's active metabolite, hydroxyfasudil, a Rho-kinase inhibitor, after subarachnoid hemorrhage (SAH) and also its effect on hemorheological abnormalities following cerebral ischemia. Chronic cerebral vasospasm was produced using a two-hemorr...