G-231A and G+70C polymorphisms of endothelin receptor type-A gene could affect the psoriasis area and severity index score and endothelin 1 levels

• Main Authors: Gökhan Okan (Author), Zeynep Yildiz (Author), Gonca Gökdemir (Author), Eda Yorulmaz (Author), Pervin Vural (Author), Semra Dogru-Abbasoglu (Author), Müjdat Uysal (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The etiopathogenesis of psoriasis has not been clearly elucidated although the role of chronic inflammation, imbalance between pro- and anti-inflammatory cytokines, and many immunological events have been established. Endothelin 1 (EDN1) and endothelin receptor type-A (EDNRA) are implica...